4QE3

Crystal structure of Antigen 85C-H260Q mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Diacylglycerol acyltransferase/mycolyltransferase Ag85C	polymer	302	33061.6	1	UniProt (P9WQN9) Pfam (PF00756)	Mycobacterium tuberculosis	DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex C, 85C, Ag85C, Fibronectin-binding protein C, Fbps C
2	B (A)	CHAPSO	non-polymer		631.9	1	Chemie (1N7) PubChem (16402373) PubChem (44119969) PubChem (44660322) PubChem (23636791) PubChem (23639399) PubChem (122146) PubChem (53393747) PubChem (50987332) PubChem (71464051) PubChem (3253739) PubChem (71305076) PubChem (90479263) PubChem (96545191) PubChem (124745618) PubChem (124901558) PubChem (124905421) PubChem (125027410) PubChem (10009199) PubChem (96327541) PubChem (96327542) PubChem (96327543) PubChem (96327544) PubChem (96545192) PubChem (102565431) PubChem (121392376) PubChem (122130148) PubChem (9895487) PubChem (144605089) PubChem (124901556) PubChem (124901561) PubChem (124901563) PubChem (124905422) PubChem (125027411) PubChem (129537355) PubChem (129537356) PubChem (145705472) PubChem (146030291) PubChem (146159852)
3	C (A)	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
4	D (A)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A: 0 - 294 (UniProt: P9WQN9)

PDB	External Database	Details
Met -1	-	expression tag
Gln 260	His 306	engineered mutation
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33061.6
Non-Polymers*	Number of molecules	2
	Total formula weight	691.9
All*	Total formula weight	33753.5

*Water molecules are not included.