4QBQ
Crystal structure of DNMT3a ADD domain bound to H3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | DNA (cytosine-5)-methyltransferase 3A | polymer | 137 | 15386.8 | 2 | UniProt (Q9Y6K1) Pfam (PF17980) Pfam (PF21255) | Homo sapiens (human) | Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA |
| 2 | C (P) | Histone H3 | polymer | 8 | 934.1 | 1 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 3 | D, E, F, G, H... (A, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | J, K, L (A, C, P) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, C: 479 - 610 (UniProt: Q9Y6K1)
| PDB | External Database | Details |
|---|---|---|
| Gly 474 | - | expression tag |
| Pro 475 | - | expression tag |
| Leu 476 | - | expression tag |
| Gly 477 | - | expression tag |
| Ser 478 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 31707.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 32100.1 |
