4QBB
Structure of the foot-and-mouth disease virus leader proteinase in complex with inhibitor (N~2~-[(3S)-4-({(2R)-1-[(4-CARBAMIMIDAMIDOBUTYL)AMINO]-4-METHYL-1-OXOPENTAN-2-YL}AMINO)-3-HYDROXY-4-OXOBUTANOYL]-L-ARGINYL-L-PROLINAMIDE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Leader protease | polymer | 167 | 19055.3 | 3 | UniProt (P03305) Pfam (PF05408) | Foot-and-mouth disease virus (FMDV) | Genome polyprotein |
| 2 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | E, F, G (A, B, C) | N~2~-[(3S)-4-({(2R)-1-[(4-carbamimidamidobutyl)amino]-4-methyl-1-oxopentan-2-yl}amino)-3-hydroxy-4-oxobutanoyl]-L-arginyl-L-prolinamide | non-polymer | 611.7 | 3 | Chemie (E69) | |||
| 4 | H (C) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | I, J, K (A, B, C) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A, B, C: 29 - 195 (UniProt: P03305)
| PDB | External Database | Details |
|---|---|---|
| Val 126 | Met 126 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57165.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1969.3 | |
| All* | Total formula weight | 59135.2 |
