Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0016032 | biological_process | viral process |
| A | 0019082 | biological_process | viral protein processing |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0016032 | biological_process | viral process |
| B | 0019082 | biological_process | viral protein processing |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0016032 | biological_process | viral process |
| C | 0019082 | biological_process | viral protein processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 201 |
| Chain | Residue |
| A | LYS108 |
| A | LEU111 |
| A | THR113 |
| A | HOH339 |
| A | HOH340 |
| A | HOH413 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE E69 A 202 |
| Chain | Residue |
| A | CYS51 |
| A | TRP52 |
| A | GLU96 |
| A | GLY97 |
| A | GLY98 |
| A | LEU143 |
| A | GLU147 |
| A | HIS148 |
| A | ALA149 |
| A | ASP163 |
| A | ASP164 |
| A | HOH403 |
| A | HOH414 |
| A | ASN46 |
| A | ASP49 |
| A | ASN50 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE E69 B 201 |
| Chain | Residue |
| B | ASN46 |
| B | ASP49 |
| B | ASN50 |
| B | CYS51 |
| B | TRP52 |
| B | GLU96 |
| B | GLY97 |
| B | GLY98 |
| B | GLN146 |
| B | GLU147 |
| B | HIS148 |
| B | HOH356 |
| B | HOH360 |
| C | SER119 |
| C | ARG120 |
| C | HOH328 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE E69 C 201 |
| Chain | Residue |
| B | SER119 |
| B | ARG120 |
| B | THR130 |
| B | HOH370 |
| C | ASN46 |
| C | ASP49 |
| C | ASN50 |
| C | CYS51 |
| C | TRP52 |
| C | GLU96 |
| C | GLY97 |
| C | GLY98 |
| C | LEU143 |
| C | GLN146 |
| C | GLU147 |
| C | HIS148 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 C 202 |
| Chain | Residue |
| C | TYR42 |
| C | ARG61 |
| C | SER73 |
| C | HOH367 |
| C | HOH397 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | ACT_SITE: For leader protease activity |
| Chain | Residue | Details |
| A | CYS51 | |
| A | HIS148 | |
| A | ASP163 | |
| B | CYS51 | |
| B | HIS148 | |
| B | ASP163 | |
| C | CYS51 | |
| C | HIS148 | |
| C | ASP163 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 746 |
| Chain | Residue | Details |
| A | ASN46 | electrostatic stabiliser, polar interaction |
| A | CYS51 | electrostatic stabiliser, polar interaction |
| A | HIS148 | hydrogen bond acceptor, proton acceptor, proton donor |
| A | ASP163 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 746 |
| Chain | Residue | Details |
| B | ASN46 | electrostatic stabiliser, polar interaction |
| B | CYS51 | electrostatic stabiliser, polar interaction |
| B | HIS148 | hydrogen bond acceptor, proton acceptor, proton donor |
| B | ASP163 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 746 |
| Chain | Residue | Details |
| C | ASN46 | electrostatic stabiliser, polar interaction |
| C | CYS51 | electrostatic stabiliser, polar interaction |
| C | HIS148 | hydrogen bond acceptor, proton acceptor, proton donor |
| C | ASP163 | electrostatic stabiliser, hydrogen bond donor |
