4QAM

Crystal Structure of the RPGR RCC1-like domain in complex with the RPGR-interacting domain of RPGRIP1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	X-linked retinitis pigmentosa GTPase regulator	polymer	400	43553.0	1	UniProt (Q92834) Pfam (PF00415) In PDB	Homo sapiens (human)	RPGR
2	B	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	polymer	201	23185.1	1	UniProt (Q96KN7) Pfam (PF18111) In PDB	Homo sapiens (human)	RPGRIP1, RPGR-interacting protein 1
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5		water	water		18.0	322	Chemie (HOH)

Sequence modifications

A: 1 - 392 (UniProt: Q92834)

PDB	External Database	Details
Val 195	Ile 195	engineered mutation
Trp 393	-	expression tag
Ser 394	-	expression tag
His 395	-	expression tag
Pro 396	-	expression tag
Gln 397	-	expression tag
Phe 398	-	expression tag
Glu 399	-	expression tag
Lys 400	-	expression tag

B: 1091 - 1286 (UniProt: Q96KN7)

PDB	External Database	Details
Gly 1086	-	expression tag
Ala 1087	-	expression tag
Mse 1088	-	expression tag
Gly 1089	-	expression tag
Ser 1090	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66738.1
Non-Polymers*	Number of molecules	9
	Total formula weight	693.3
All*	Total formula weight	67431.3

*Water molecules are not included.