4Q9S
Crystal Structure of human Focal Adhesion Kinase (Fak) bound to Compound1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Focal adhesion kinase 1 | polymer | 281 | 32120.1 | 1 | UniProt (Q05397) Pfam (PF07714) | Homo sapiens (human) | FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK |
| 2 | B (A) | 3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1H)-one | non-polymer | 203.2 | 1 | Chemie (30G) | |||
| 3 | C (A) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 411 - 686 (UniProt: Q05397)
| PDB | External Database | Details |
|---|---|---|
| Gly 406 | - | expression tag |
| Ala 407 | - | expression tag |
| Met 408 | - | expression tag |
| Gly 409 | - | expression tag |
| Ser 410 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32120.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 203.2 | |
| All* | Total formula weight | 32323.3 |
