4Q6A
Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 160 | 18419.1 | 1 | UniProt (W7NDF6) In PDB | Staphylococcus aureus MUF168 | |
| 2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 0 - 157 (UniProt: W7NDF6)
| PDB | External Database | Details |
|---|---|---|
| Leu 31 | Val 32 | engineered mutation |
| Leu 158 | - | expression tag |
| Glu 159 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18419.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 894.5 | |
| All* | Total formula weight | 19313.6 |
