4PZV
Crystal structure of Francisella tularensis HPPK-DHPS in complex with bisubstrate analog HPPK inhibitor J1D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase | polymer | 421 | 48313.8 | 1 | UniProt (Q5NGA7) Pfam (PF01288) Pfam (PF00809) | Francisella tularensis subsp. tularensis | |
| 2 | B (A) | 5'-{[2-({N-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)carbonyl]glycyl}amino)ethyl]sulfonyl}-5'-deoxyadenosine | non-polymer | 634.6 | 1 | Chemie (J1D) | |||
| 3 | C, D, E, F, G... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | J (A) | water | water | 18.0 | 430 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48313.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1069.1 | |
| All* | Total formula weight | 49382.9 |
