4PYZ

Crystal structure of the first two Ubl domains of Deubiquitylase USP7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubiquitin carboxyl-terminal hydrolase 7	polymer	273	31733.7	2	UniProt (Q93009) Pfam (PF12436)	Homo sapiens (human)	Deubiquitinating enzyme 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7
2	C, D (B)	UNKNOWN ATOM OR ION	non-polymer			2	Chemie (UNX)
3	E, F (A, B)	water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, B: 537 - 793 (UniProt: Q93009)

PDB	External Database	Details
Ser 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag
His 527	-	expression tag
Ser 528	-	expression tag
Ser 529	-	expression tag
Gly 530	-	expression tag
Leu 531	-	expression tag
Val 532	-	expression tag
Pro 533	-	expression tag
Arg 534	-	expression tag
Gly 535	-	expression tag
Ser 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63467.4
Non-Polymers*	Number of molecules	2
	Total formula weight	0.0
All*	Total formula weight	63467.4

*Water molecules are not included.