4PY6
Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bromodomain protein, putative | polymer | 145 | 17455.8 | 4 | UniProt (Q8I240) | Plasmodium falciparum 3D7 | |
| 2 | E, G, J, K (A, B, C, D) | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 521.7 | 4 | Chemie (R78) | |||
| 3 | F, H, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1175 - 1318 (UniProt: Q8I240)
| PDB | External Database | Details |
|---|---|---|
| Gly 1174 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 69823.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2272.8 | |
| All* | Total formula weight | 72096.2 |
