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4PW8

Human tryptophan 2,3-dioxygenase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Tryptophan 2,3-dioxygenasepolymer37344139.38UniProt (P48775)
Pfam (PF03301)
Homo sapiens (human)TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase
2I
(H)
COBALT (II) IONnon-polymer58.91Chemie (CO)
3J, K, L, M, N...
(A, B, C, E, F...)
waterwater18.055Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 19 - 388 (UniProt: P48775)
PDBExternal DatabaseDetails
Ser 16-expression tag
Asn 17-expression tag
Ala 18-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight353114.4
Non-Polymers*Number of molecules1
Total formula weight58.9
All*Total formula weight353173.3
*Water molecules are not included.

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PDB entries from 2025-12-17

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