4PSX
Crystal structure of histone acetyltransferase complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Histone acetyltransferase type B catalytic subunit | polymer | 320 | 37566.3 | 2 | UniProt (Q12341) Pfam (PF10394) Pfam (PF00583) Pfam (PF21184) | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | B, E (B, E) | Histone acetyltransferase type B subunit 2 | polymer | 401 | 45107.9 | 2 | UniProt (P39984) Pfam (PF12265) Pfam (PF00400) | Saccharomyces cerevisiae (Baker's yeast) | |
| 3 | C, F (C, F) | Histone H4 | polymer | 48 | 5093.1 | 2 | UniProt (P02309) Pfam (PF15511) | Saccharomyces cerevisiae (Baker's yeast) | |
| 4 | G, H (Y, P) | Histone H3 | polymer | 15 | 1565.8 | 2 | UniProt (P61830) | Saccharomyces cerevisiae S288c (Baker's yeast) | |
| 5 | I, K (A, D) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 6 | J (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 606 | Chemie (HOH) |
Sequence modifications
A, D: 7 - 319 (UniProt: Q12341)
B, E: 8 - 389 (UniProt: P39984)
C, F: 1 - 48 (UniProt: P02309)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Asn 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Phe 6 | - | expression tag |
| Ser 320 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Asn 3 | - | expression tag |
| Gln 4 | - | expression tag |
| Glu 5 | - | expression tag |
| Lys 6 | - | expression tag |
| Pro 7 | - | expression tag |
| Thr 143 | Val 143 | engineered mutation |
| Gly 390 | - | expression tag |
| Gly 391 | - | expression tag |
| Pro 392 | - | expression tag |
| Pro 393 | - | expression tag |
| Lys 394 | - | expression tag |
| Val 395 | - | expression tag |
| Asn 396 | - | expression tag |
| Lys 397 | - | expression tag |
| Asp 398 | - | expression tag |
| Ile 399 | - | expression tag |
| Ile 400 | - | expression tag |
| Ser 401 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 21 | Ile 22 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 178666.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1631.1 | |
| All* | Total formula weight | 180297.4 |
