4PS1
Caspase-8 specific unnatural amino acid peptides
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Caspase-8 | polymer | 275 | 31447.6 | 4 | UniProt (Q14790) Pfam (PF00656) In PDB | Homo sapiens (human) | CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH, Caspase-8 subunit p18, Caspase-8 subunit p10 |
2 | E, F, G, H | (BAL)LQ(HYP)(1U8) PEPTIDE | polymer | 5 | 704.8 | 4 | |||
3 | A, B, C, D | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 4 | Chemie (DTT) | |||
4 | water | water | 18.0 | 855 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 217 - 479 (UniProt: Q14790)
PDB | External Database | Details |
---|---|---|
Met 216 | - | expression tag |
Ala 480 | - | expression tag |
Ala 481 | - | expression tag |
Ala 482 | - | expression tag |
Leu 483 | - | expression tag |
Glu 484 | - | expression tag |
His 485 | - | expression tag |
His 486 | - | expression tag |
His 487 | - | expression tag |
His 488 | - | expression tag |
His 489 | - | expression tag |
His 490 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 128609.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 617.0 | |
All* | Total formula weight | 129226.5 |