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4PP3

Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 6-methyl UAB30 and the coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARetinoic acid receptor RXR-alphapolymer23125897.01UniProt (P19793)
Pfam (PF00104)
In PDB
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha
2BNuclear receptor coactivator 2polymer131579.91UniProt (Q15596)
In PDB
Homo sapiensNCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3A(2E,4E,6Z,8E)-3,7-dimethyl-8-(6-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acidnon-polymer308.41Chemie (2VZ)
4waterwater18.0120Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27476.9
Non-Polymers*Number of molecules1
Total formula weight308.4
All*Total formula weight27785.3
*Water molecules are not included.

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PDB entries from 2024-06-12

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