4PP3
Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 6-methyl UAB30 and the coactivator peptide GRIP-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Retinoic acid receptor RXR-alpha | polymer | 231 | 25897.0 | 1 | UniProt (P19793) Pfam (PF00104) In PDB | Homo sapiens (human) | Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha |
2 | B | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) In PDB | Homo sapiens | NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2 |
3 | A | (2E,4E,6Z,8E)-3,7-dimethyl-8-(6-methyl-3,4-dihydronaphthalen-1(2H)-ylidene)octa-2,4,6-trienoic acid | non-polymer | 308.4 | 1 | Chemie (2VZ) | |||
4 | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27476.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 308.4 | |
All* | Total formula weight | 27785.3 |