4POL
Crystal structures of thioredoxin with mesna at 2.8A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Thioredoxin | polymer | 109 | 12051.1 | 4 | UniProt (P10599) Pfam (PF00085) | Homo sapiens (human) | Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP |
| 2 | E, F, G, H (A, B) | 1-THIOETHANESULFONIC ACID | non-polymer | 142.2 | 4 | Chemie (COM) |
Sequence modifications
A, B, C, D: 1 - 105 (UniProt: P10599)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
| Lys 13 | Glu 13 | engineered mutation |
| Lys 16 | Asp 16 | engineered mutation |
| Lys 95 | Glu 95 | engineered mutation |
| Lys 103 | Glu 103 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48204.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 568.8 | |
| All* | Total formula weight | 48773.0 |
