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4PMF

Human transthyretin (TTR) complexed with curcumin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer11712832.42UniProt (P02766)
Pfam (PF00576)
Homo sapiens (Human)ATTR,Prealbumin,TBPA
2C, E
(A, B)
(1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-onenon-polymer368.42Chemie (CUR)
3D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
4F
(B)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5G, H
(A, B)
waterwater18.0220Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight25664.8
Non-Polymers*Number of molecules4
Total formula weight821.8
All*Total formula weight26486.6
*Water molecules are not included.

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PDB entries from 2025-06-25

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