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4PL8

Structure of rabbit skeletal muscle actin in complex with a hybrid peptide comprising thymosin beta4 and the lysine-rich region of Cordon-Bleu

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
Actin, alpha skeletal musclepolymer37541875.62UniProt (P68135)
Pfam (PF00022)
Oryctolagus cuniculus (Rabbit)Alpha-actin-1
2B
(H)
Thymosin beta-4,Protein cordon-bleu,Thymosin beta-4polymer738333.41UniProt (P62328)
UniProt (O75128)
Pfam (PF01290)
Homo sapiensT beta-4,Fx,T beta-4,Fx
3D, F
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
4E, G
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
5H, I, J
(A, H, B)
waterwater18.0531Chemie (HOH)
Sequence modifications
H: 3 - 18 (UniProt: P62328)
PDBExternal DatabaseDetails
Gly 1-insertion
Pro 2-insertion
H: 19 - 30 (UniProt: O75128)
H: 31 - 73 (UniProt: P62328)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight92084.7
Non-Polymers*Number of molecules4
Total formula weight1094.5
All*Total formula weight93179.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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