4PK7

crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cohesin subunit SA-2	polymer	994	114980.6	1	UniProt (Q8N3U4) Pfam (PF08514) Pfam (PF21581)	Homo sapiens (Human)	SCC3 homolog 2,Stromal antigen 2
2	B (B)	Double-strand-break repair protein rad21 homolog	polymer	148	16772.4	1	UniProt (O60216)	Homo sapiens (Human)	hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog
3	C (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)

Sequence modifications

A: 80 - 1060 (UniProt: Q8N3U4)

PDB	External Database	Details
Gly 67	-	expression tag
Ala 68	-	expression tag
Met 69	-	expression tag
Asp 70	-	expression tag
Pro 71	-	expression tag
Glu 72	-	expression tag
Phe 73	-	expression tag
Gly 74	-	expression tag
Arg 75	-	expression tag
Pro 76	-	expression tag
Gly 77	-	expression tag
Arg 78	-	expression tag
Pro 79	-	expression tag

B: 281 - 420 (UniProt: O60216)

PDB	External Database	Details
Gly 273	-	expression tag
Pro 274	-	expression tag
Leu 275	-	expression tag
Gly 276	-	expression tag
Ser 277	-	expression tag
Gly 278	-	expression tag
Arg 279	-	expression tag
Pro 280	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	131753.0
Non-Polymers*	Number of molecules	1
	Total formula weight	195.2
All*	Total formula weight	131948.3

*Water molecules are not included.