4PK7
crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1) with bound MES, native proteins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cohesin subunit SA-2 | polymer | 994 | 114980.6 | 1 | UniProt (Q8N3U4) Pfam (PF08514) Pfam (PF21581) Pfam (PF24571) | Homo sapiens (Human) | SCC3 homolog 2,Stromal antigen 2 |
| 2 | B (B) | Double-strand-break repair protein rad21 homolog | polymer | 148 | 16772.4 | 1 | UniProt (O60216) | Homo sapiens (Human) | hHR21,Nuclear matrix protein 1,NXP-1,SCC1 homolog |
| 3 | C (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) |
Sequence modifications
A: 80 - 1060 (UniProt: Q8N3U4)
B: 281 - 420 (UniProt: O60216)
| PDB | External Database | Details |
|---|---|---|
| Gly 67 | - | expression tag |
| Ala 68 | - | expression tag |
| Met 69 | - | expression tag |
| Asp 70 | - | expression tag |
| Pro 71 | - | expression tag |
| Glu 72 | - | expression tag |
| Phe 73 | - | expression tag |
| Gly 74 | - | expression tag |
| Arg 75 | - | expression tag |
| Pro 76 | - | expression tag |
| Gly 77 | - | expression tag |
| Arg 78 | - | expression tag |
| Pro 79 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 273 | - | expression tag |
| Pro 274 | - | expression tag |
| Leu 275 | - | expression tag |
| Gly 276 | - | expression tag |
| Ser 277 | - | expression tag |
| Gly 278 | - | expression tag |
| Arg 279 | - | expression tag |
| Pro 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 131753.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 195.2 | |
| All* | Total formula weight | 131948.3 |
