4PJO
Minimal U1 snRNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, a, O, o | Small nuclear ribonucleoprotein Sm D3 | polymer | 126 | 13940.3 | 4 | UniProt (P62318) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D3,snRNP core protein D3 |
| 2 | B, b, P, p | Small nuclear ribonucleoprotein-associated proteins B and B' | polymer | 95 | 10911.9 | 4 | UniProt (P14678) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-B,Sm protein B/B',SmB/B' |
| 3 | C, c, Q, q | Small nuclear ribonucleoprotein Sm D1 | polymer | 91 | 10026.6 | 4 | UniProt (P62314) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D1,Sm-D autoantigen,snRNP core protein D1 |
| 4 | D, d, R, r | Small nuclear ribonucleoprotein Sm D2 | polymer | 118 | 13551.9 | 4 | UniProt (P62316) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D2,snRNP core protein D2 |
| 5 | E, e, S, s | Small nuclear ribonucleoprotein E | polymer | 92 | 10817.6 | 4 | UniProt (P62304) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-E,Sm protein E,SmE |
| 6 | F, f, T, t | Small nuclear ribonucleoprotein F | polymer | 75 | 8369.8 | 4 | UniProt (P62306) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-F,Sm protein F,SmF |
| 7 | G, g, U, u | Small nuclear ribonucleoprotein G | polymer | 76 | 8508.1 | 4 | UniProt (P62308) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-G,Sm protein G,SmG |
| 8 | K, k, N, n | U1 small nuclear ribonucleoprotein 70 kDa | polymer | 60 | 6862.8 | 4 | UniProt (P08621) Pfam (PF12220) In PDB | Homo sapiens (Human) | snRNP70 |
| 9 | L, l, M, m | U1 small nuclear ribonucleoprotein C | polymer | 61 | 7279.2 | 4 | UniProt (P09234) Pfam (PF06220) In PDB | Homo sapiens (Human) | U1C |
| 10 | 1, 2, 3, 4 | U1 RNA variant (48-MER) with 4-helix junction replaced by kissing loop (HIV-1 (Mal) DIS) and shorter stem-loop 4. | polymer | 60 | 19575.5 | 4 | Homo sapiens | ||
| 11 | X, x, Y, y | RNA (5'-R(*AP*GP*GP*UP*AP*AP*GP*UP*CP*C)-3') | polymer | 10 | 3201.0 | 4 | Homo sapiens | ||
| 12 | l, M, L, m | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 13 | 2, 1 | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 14 | 1, l, 2, 3, 4... | MAGNESIUM ION | non-polymer | 24.3 | 20 | Chemie (MG) | |||
| 15 | 1, b, Q, 3 | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 16 | 4 | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
| 17 | 4 | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 18 | y | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 19 | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
C, c, Q, q: 2 - 85 (UniProt: P62314)
K, k, N, n: 2 - 60 (UniProt: P08621)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | linker |
| Ser -4 | - | linker |
| Gly -3 | - | linker |
| Ser -2 | - | linker |
| Gly -1 | - | linker |
| Ser 0 | - | linker |
| Val 1 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 44 |
| Total formula weight | 452179.4 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 1636.5 | |
| All* | Total formula weight | 453815.9 |
