4PJO

Minimal U1 snRNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000243	cellular_component	commitment complex
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000245	biological_process	spliceosomal complex assembly
A	0000387	biological_process	spliceosomal snRNP assembly
A	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0005683	cellular_component	U7 snRNP
A	0005684	cellular_component	U2-type spliceosomal complex
A	0005685	cellular_component	U1 snRNP
A	0005686	cellular_component	U2 snRNP
A	0005687	cellular_component	U4 snRNP
A	0005689	cellular_component	U12-type spliceosomal complex
A	0005697	cellular_component	telomerase holoenzyme complex
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006396	biological_process	RNA processing
A	0006397	biological_process	mRNA processing
A	0006479	biological_process	protein methylation
A	0008380	biological_process	RNA splicing
A	0016604	cellular_component	nuclear body
A	0019899	molecular_function	enzyme binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0034709	cellular_component	methylosome
A	0034715	cellular_component	pICln-Sm protein complex
A	0034719	cellular_component	SMN-Sm protein complex
A	0036261	biological_process	7-methylguanosine cap hypermethylation
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0070034	molecular_function	telomerase RNA binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071011	cellular_component	precatalytic spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071045	biological_process	nuclear histone mRNA catabolic process
A	0071208	molecular_function	histone pre-mRNA DCP binding
A	0071209	molecular_function	U7 snRNA binding
A	0097526	cellular_component	spliceosomal tri-snRNP complex
A	1903241	biological_process	U2-type prespliceosome assembly
A	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
C	0000387	biological_process	spliceosomal snRNP assembly
C	0003723	molecular_function	RNA binding
C	0006396	biological_process	RNA processing
D	0000244	biological_process	spliceosomal tri-snRNP complex assembly
D	0000245	biological_process	spliceosomal complex assembly
D	0000387	biological_process	spliceosomal snRNP assembly
D	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0005684	cellular_component	U2-type spliceosomal complex
D	0005685	cellular_component	U1 snRNP
D	0005686	cellular_component	U2 snRNP
D	0005687	cellular_component	U4 snRNP
D	0005689	cellular_component	U12-type spliceosomal complex
D	0005829	cellular_component	cytosol
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0030532	cellular_component	small nuclear ribonucleoprotein complex
D	0034709	cellular_component	methylosome
D	0034715	cellular_component	pICln-Sm protein complex
D	0034719	cellular_component	SMN-Sm protein complex
D	0036261	biological_process	7-methylguanosine cap hypermethylation
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
D	0070062	cellular_component	extracellular exosome
D	0071005	cellular_component	U2-type precatalytic spliceosome
D	0071007	cellular_component	U2-type catalytic step 2 spliceosome
D	0071011	cellular_component	precatalytic spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
D	0097525	cellular_component	spliceosomal snRNP complex
D	1903241	biological_process	U2-type prespliceosome assembly
D	1990904	cellular_component	ribonucleoprotein complex
E	0000244	biological_process	spliceosomal tri-snRNP complex assembly
E	0000245	biological_process	spliceosomal complex assembly
E	0000387	biological_process	spliceosomal snRNP assembly
E	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005683	cellular_component	U7 snRNP
E	0005684	cellular_component	U2-type spliceosomal complex
E	0005685	cellular_component	U1 snRNP
E	0005686	cellular_component	U2 snRNP
E	0005687	cellular_component	U4 snRNP
E	0005689	cellular_component	U12-type spliceosomal complex
E	0005697	cellular_component	telomerase holoenzyme complex
E	0005829	cellular_component	cytosol
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0030532	cellular_component	small nuclear ribonucleoprotein complex
E	0034709	cellular_component	methylosome
E	0034715	cellular_component	pICln-Sm protein complex
E	0034719	cellular_component	SMN-Sm protein complex
E	0036261	biological_process	7-methylguanosine cap hypermethylation
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
E	0071005	cellular_component	U2-type precatalytic spliceosome
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071011	cellular_component	precatalytic spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	0071045	biological_process	nuclear histone mRNA catabolic process
E	1903241	biological_process	U2-type prespliceosome assembly
E	1990904	cellular_component	ribonucleoprotein complex
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003723	molecular_function	RNA binding
F	0005681	cellular_component	spliceosomal complex
G	0000244	biological_process	spliceosomal tri-snRNP complex assembly
G	0000245	biological_process	spliceosomal complex assembly
G	0000387	biological_process	spliceosomal snRNP assembly
G	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005681	cellular_component	spliceosomal complex
G	0005682	cellular_component	U5 snRNP
G	0005683	cellular_component	U7 snRNP
G	0005684	cellular_component	U2-type spliceosomal complex
G	0005685	cellular_component	U1 snRNP
G	0005686	cellular_component	U2 snRNP
G	0005687	cellular_component	U4 snRNP
G	0005689	cellular_component	U12-type spliceosomal complex
G	0005829	cellular_component	cytosol
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0030532	cellular_component	small nuclear ribonucleoprotein complex
G	0034709	cellular_component	methylosome
G	0034719	cellular_component	SMN-Sm protein complex
G	0036261	biological_process	7-methylguanosine cap hypermethylation
G	0043186	cellular_component	P granule
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
G	0071004	cellular_component	U2-type prespliceosome
G	0071005	cellular_component	U2-type precatalytic spliceosome
G	0071007	cellular_component	U2-type catalytic step 2 spliceosome
G	0071011	cellular_component	precatalytic spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	0071045	biological_process	nuclear histone mRNA catabolic process
G	0097526	cellular_component	spliceosomal tri-snRNP complex
G	1903241	biological_process	U2-type prespliceosome assembly
G	1990904	cellular_component	ribonucleoprotein complex
L	0000395	biological_process	mRNA 5'-splice site recognition
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0003676	molecular_function	nucleic acid binding
L	0005634	cellular_component	nucleus
L	0005685	cellular_component	U1 snRNP
L	0008270	molecular_function	zinc ion binding
L	0030627	molecular_function	pre-mRNA 5'-splice site binding
M	0000395	biological_process	mRNA 5'-splice site recognition
M	0000398	biological_process	mRNA splicing, via spliceosome
M	0003676	molecular_function	nucleic acid binding
M	0005634	cellular_component	nucleus
M	0005685	cellular_component	U1 snRNP
M	0008270	molecular_function	zinc ion binding
M	0030627	molecular_function	pre-mRNA 5'-splice site binding
O	0000243	cellular_component	commitment complex
O	0000244	biological_process	spliceosomal tri-snRNP complex assembly
O	0000245	biological_process	spliceosomal complex assembly
O	0000387	biological_process	spliceosomal snRNP assembly
O	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005681	cellular_component	spliceosomal complex
O	0005682	cellular_component	U5 snRNP
O	0005683	cellular_component	U7 snRNP
O	0005684	cellular_component	U2-type spliceosomal complex
O	0005685	cellular_component	U1 snRNP
O	0005686	cellular_component	U2 snRNP
O	0005687	cellular_component	U4 snRNP
O	0005689	cellular_component	U12-type spliceosomal complex
O	0005697	cellular_component	telomerase holoenzyme complex
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006396	biological_process	RNA processing
O	0006397	biological_process	mRNA processing
O	0006479	biological_process	protein methylation
O	0008380	biological_process	RNA splicing
O	0016604	cellular_component	nuclear body
O	0019899	molecular_function	enzyme binding
O	0030532	cellular_component	small nuclear ribonucleoprotein complex
O	0034709	cellular_component	methylosome
O	0034715	cellular_component	pICln-Sm protein complex
O	0034719	cellular_component	SMN-Sm protein complex
O	0036261	biological_process	7-methylguanosine cap hypermethylation
O	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
O	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
O	0070034	molecular_function	telomerase RNA binding
O	0071005	cellular_component	U2-type precatalytic spliceosome
O	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0071011	cellular_component	precatalytic spliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	0071045	biological_process	nuclear histone mRNA catabolic process
O	0071208	molecular_function	histone pre-mRNA DCP binding
O	0071209	molecular_function	U7 snRNA binding
O	0097526	cellular_component	spliceosomal tri-snRNP complex
O	1903241	biological_process	U2-type prespliceosome assembly
O	1990904	cellular_component	ribonucleoprotein complex
P	0003723	molecular_function	RNA binding
Q	0000387	biological_process	spliceosomal snRNP assembly
Q	0003723	molecular_function	RNA binding
Q	0006396	biological_process	RNA processing
R	0000244	biological_process	spliceosomal tri-snRNP complex assembly
R	0000245	biological_process	spliceosomal complex assembly
R	0000387	biological_process	spliceosomal snRNP assembly
R	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0005682	cellular_component	U5 snRNP
R	0005684	cellular_component	U2-type spliceosomal complex
R	0005685	cellular_component	U1 snRNP
R	0005686	cellular_component	U2 snRNP
R	0005687	cellular_component	U4 snRNP
R	0005689	cellular_component	U12-type spliceosomal complex
R	0005829	cellular_component	cytosol
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
R	0030532	cellular_component	small nuclear ribonucleoprotein complex
R	0034709	cellular_component	methylosome
R	0034715	cellular_component	pICln-Sm protein complex
R	0034719	cellular_component	SMN-Sm protein complex
R	0036261	biological_process	7-methylguanosine cap hypermethylation
R	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
R	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
R	0070062	cellular_component	extracellular exosome
R	0071005	cellular_component	U2-type precatalytic spliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071011	cellular_component	precatalytic spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
R	0097525	cellular_component	spliceosomal snRNP complex
R	1903241	biological_process	U2-type prespliceosome assembly
R	1990904	cellular_component	ribonucleoprotein complex
S	0000244	biological_process	spliceosomal tri-snRNP complex assembly
S	0000245	biological_process	spliceosomal complex assembly
S	0000387	biological_process	spliceosomal snRNP assembly
S	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005681	cellular_component	spliceosomal complex
S	0005682	cellular_component	U5 snRNP
S	0005683	cellular_component	U7 snRNP
S	0005684	cellular_component	U2-type spliceosomal complex
S	0005685	cellular_component	U1 snRNP
S	0005686	cellular_component	U2 snRNP
S	0005687	cellular_component	U4 snRNP
S	0005689	cellular_component	U12-type spliceosomal complex
S	0005697	cellular_component	telomerase holoenzyme complex
S	0005829	cellular_component	cytosol
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0030532	cellular_component	small nuclear ribonucleoprotein complex
S	0034709	cellular_component	methylosome
S	0034715	cellular_component	pICln-Sm protein complex
S	0034719	cellular_component	SMN-Sm protein complex
S	0036261	biological_process	7-methylguanosine cap hypermethylation
S	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
S	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
S	0071005	cellular_component	U2-type precatalytic spliceosome
S	0071007	cellular_component	U2-type catalytic step 2 spliceosome
S	0071011	cellular_component	precatalytic spliceosome
S	0071013	cellular_component	catalytic step 2 spliceosome
S	0071045	biological_process	nuclear histone mRNA catabolic process
S	1903241	biological_process	U2-type prespliceosome assembly
S	1990904	cellular_component	ribonucleoprotein complex
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0003723	molecular_function	RNA binding
T	0005681	cellular_component	spliceosomal complex
U	0000244	biological_process	spliceosomal tri-snRNP complex assembly
U	0000245	biological_process	spliceosomal complex assembly
U	0000387	biological_process	spliceosomal snRNP assembly
U	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0003723	molecular_function	RNA binding
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005681	cellular_component	spliceosomal complex
U	0005682	cellular_component	U5 snRNP
U	0005683	cellular_component	U7 snRNP
U	0005684	cellular_component	U2-type spliceosomal complex
U	0005685	cellular_component	U1 snRNP
U	0005686	cellular_component	U2 snRNP
U	0005687	cellular_component	U4 snRNP
U	0005689	cellular_component	U12-type spliceosomal complex
U	0005829	cellular_component	cytosol
U	0006397	biological_process	mRNA processing
U	0008380	biological_process	RNA splicing
U	0030532	cellular_component	small nuclear ribonucleoprotein complex
U	0034709	cellular_component	methylosome
U	0034719	cellular_component	SMN-Sm protein complex
U	0036261	biological_process	7-methylguanosine cap hypermethylation
U	0043186	cellular_component	P granule
U	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
U	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
U	0071004	cellular_component	U2-type prespliceosome
U	0071005	cellular_component	U2-type precatalytic spliceosome
U	0071007	cellular_component	U2-type catalytic step 2 spliceosome
U	0071011	cellular_component	precatalytic spliceosome
U	0071013	cellular_component	catalytic step 2 spliceosome
U	0071045	biological_process	nuclear histone mRNA catabolic process
U	0097526	cellular_component	spliceosomal tri-snRNP complex
U	1903241	biological_process	U2-type prespliceosome assembly
U	1990904	cellular_component	ribonucleoprotein complex
a	0000243	cellular_component	commitment complex
a	0000244	biological_process	spliceosomal tri-snRNP complex assembly
a	0000245	biological_process	spliceosomal complex assembly
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005683	cellular_component	U7 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005697	cellular_component	telomerase holoenzyme complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006396	biological_process	RNA processing
a	0006397	biological_process	mRNA processing
a	0006479	biological_process	protein methylation
a	0008380	biological_process	RNA splicing
a	0016604	cellular_component	nuclear body
a	0019899	molecular_function	enzyme binding
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
a	0070034	molecular_function	telomerase RNA binding
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0071045	biological_process	nuclear histone mRNA catabolic process
a	0071208	molecular_function	histone pre-mRNA DCP binding
a	0071209	molecular_function	U7 snRNA binding
a	0097526	cellular_component	spliceosomal tri-snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990904	cellular_component	ribonucleoprotein complex
b	0003723	molecular_function	RNA binding
c	0000387	biological_process	spliceosomal snRNP assembly
c	0003723	molecular_function	RNA binding
c	0006396	biological_process	RNA processing
d	0000244	biological_process	spliceosomal tri-snRNP complex assembly
d	0000245	biological_process	spliceosomal complex assembly
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005829	cellular_component	cytosol
d	0006397	biological_process	mRNA processing
d	0008380	biological_process	RNA splicing
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
d	0070062	cellular_component	extracellular exosome
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0097525	cellular_component	spliceosomal snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0000244	biological_process	spliceosomal tri-snRNP complex assembly
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	0071045	biological_process	nuclear histone mRNA catabolic process
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990904	cellular_component	ribonucleoprotein complex
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005681	cellular_component	spliceosomal complex
g	0000244	biological_process	spliceosomal tri-snRNP complex assembly
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043186	cellular_component	P granule
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
g	0071004	cellular_component	U2-type prespliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0071045	biological_process	nuclear histone mRNA catabolic process
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
g	1990904	cellular_component	ribonucleoprotein complex
l	0000395	biological_process	mRNA 5'-splice site recognition
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003676	molecular_function	nucleic acid binding
l	0005634	cellular_component	nucleus
l	0005685	cellular_component	U1 snRNP
l	0008270	molecular_function	zinc ion binding
l	0030627	molecular_function	pre-mRNA 5'-splice site binding
m	0000395	biological_process	mRNA 5'-splice site recognition
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003676	molecular_function	nucleic acid binding
m	0005634	cellular_component	nucleus
m	0005685	cellular_component	U1 snRNP
m	0008270	molecular_function	zinc ion binding
m	0030627	molecular_function	pre-mRNA 5'-splice site binding
o	0000243	cellular_component	commitment complex
o	0000244	biological_process	spliceosomal tri-snRNP complex assembly
o	0000245	biological_process	spliceosomal complex assembly
o	0000387	biological_process	spliceosomal snRNP assembly
o	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
o	0000398	biological_process	mRNA splicing, via spliceosome
o	0003723	molecular_function	RNA binding
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005681	cellular_component	spliceosomal complex
o	0005682	cellular_component	U5 snRNP
o	0005683	cellular_component	U7 snRNP
o	0005684	cellular_component	U2-type spliceosomal complex
o	0005685	cellular_component	U1 snRNP
o	0005686	cellular_component	U2 snRNP
o	0005687	cellular_component	U4 snRNP
o	0005689	cellular_component	U12-type spliceosomal complex
o	0005697	cellular_component	telomerase holoenzyme complex
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0006396	biological_process	RNA processing
o	0006397	biological_process	mRNA processing
o	0006479	biological_process	protein methylation
o	0008380	biological_process	RNA splicing
o	0016604	cellular_component	nuclear body
o	0019899	molecular_function	enzyme binding
o	0030532	cellular_component	small nuclear ribonucleoprotein complex
o	0034709	cellular_component	methylosome
o	0034715	cellular_component	pICln-Sm protein complex
o	0034719	cellular_component	SMN-Sm protein complex
o	0036261	biological_process	7-methylguanosine cap hypermethylation
o	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
o	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
o	0070034	molecular_function	telomerase RNA binding
o	0071005	cellular_component	U2-type precatalytic spliceosome
o	0071007	cellular_component	U2-type catalytic step 2 spliceosome
o	0071011	cellular_component	precatalytic spliceosome
o	0071013	cellular_component	catalytic step 2 spliceosome
o	0071045	biological_process	nuclear histone mRNA catabolic process
o	0071208	molecular_function	histone pre-mRNA DCP binding
o	0071209	molecular_function	U7 snRNA binding
o	0097526	cellular_component	spliceosomal tri-snRNP complex
o	1903241	biological_process	U2-type prespliceosome assembly
o	1990904	cellular_component	ribonucleoprotein complex
p	0003723	molecular_function	RNA binding
q	0000387	biological_process	spliceosomal snRNP assembly
q	0003723	molecular_function	RNA binding
q	0006396	biological_process	RNA processing
r	0000244	biological_process	spliceosomal tri-snRNP complex assembly
r	0000245	biological_process	spliceosomal complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0005681	cellular_component	spliceosomal complex
r	0005682	cellular_component	U5 snRNP
r	0005684	cellular_component	U2-type spliceosomal complex
r	0005685	cellular_component	U1 snRNP
r	0005686	cellular_component	U2 snRNP
r	0005687	cellular_component	U4 snRNP
r	0005689	cellular_component	U12-type spliceosomal complex
r	0005829	cellular_component	cytosol
r	0006397	biological_process	mRNA processing
r	0008380	biological_process	RNA splicing
r	0030532	cellular_component	small nuclear ribonucleoprotein complex
r	0034709	cellular_component	methylosome
r	0034715	cellular_component	pICln-Sm protein complex
r	0034719	cellular_component	SMN-Sm protein complex
r	0036261	biological_process	7-methylguanosine cap hypermethylation
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
r	0070062	cellular_component	extracellular exosome
r	0071005	cellular_component	U2-type precatalytic spliceosome
r	0071007	cellular_component	U2-type catalytic step 2 spliceosome
r	0071011	cellular_component	precatalytic spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0097525	cellular_component	spliceosomal snRNP complex
r	1903241	biological_process	U2-type prespliceosome assembly
r	1990904	cellular_component	ribonucleoprotein complex
s	0000244	biological_process	spliceosomal tri-snRNP complex assembly
s	0000245	biological_process	spliceosomal complex assembly
s	0000387	biological_process	spliceosomal snRNP assembly
s	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0003723	molecular_function	RNA binding
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0005681	cellular_component	spliceosomal complex
s	0005682	cellular_component	U5 snRNP
s	0005683	cellular_component	U7 snRNP
s	0005684	cellular_component	U2-type spliceosomal complex
s	0005685	cellular_component	U1 snRNP
s	0005686	cellular_component	U2 snRNP
s	0005687	cellular_component	U4 snRNP
s	0005689	cellular_component	U12-type spliceosomal complex
s	0005697	cellular_component	telomerase holoenzyme complex
s	0005829	cellular_component	cytosol
s	0006397	biological_process	mRNA processing
s	0008380	biological_process	RNA splicing
s	0030532	cellular_component	small nuclear ribonucleoprotein complex
s	0034709	cellular_component	methylosome
s	0034715	cellular_component	pICln-Sm protein complex
s	0034719	cellular_component	SMN-Sm protein complex
s	0036261	biological_process	7-methylguanosine cap hypermethylation
s	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
s	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
s	0071005	cellular_component	U2-type precatalytic spliceosome
s	0071007	cellular_component	U2-type catalytic step 2 spliceosome
s	0071011	cellular_component	precatalytic spliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
s	0071045	biological_process	nuclear histone mRNA catabolic process
s	1903241	biological_process	U2-type prespliceosome assembly
s	1990904	cellular_component	ribonucleoprotein complex
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0003723	molecular_function	RNA binding
t	0005681	cellular_component	spliceosomal complex
u	0000244	biological_process	spliceosomal tri-snRNP complex assembly
u	0000245	biological_process	spliceosomal complex assembly
u	0000387	biological_process	spliceosomal snRNP assembly
u	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0003723	molecular_function	RNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005681	cellular_component	spliceosomal complex
u	0005682	cellular_component	U5 snRNP
u	0005683	cellular_component	U7 snRNP
u	0005684	cellular_component	U2-type spliceosomal complex
u	0005685	cellular_component	U1 snRNP
u	0005686	cellular_component	U2 snRNP
u	0005687	cellular_component	U4 snRNP
u	0005689	cellular_component	U12-type spliceosomal complex
u	0005829	cellular_component	cytosol
u	0006397	biological_process	mRNA processing
u	0008380	biological_process	RNA splicing
u	0030532	cellular_component	small nuclear ribonucleoprotein complex
u	0034709	cellular_component	methylosome
u	0034719	cellular_component	SMN-Sm protein complex
u	0036261	biological_process	7-methylguanosine cap hypermethylation
u	0043186	cellular_component	P granule
u	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
u	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
u	0071004	cellular_component	U2-type prespliceosome
u	0071005	cellular_component	U2-type precatalytic spliceosome
u	0071007	cellular_component	U2-type catalytic step 2 spliceosome
u	0071011	cellular_component	precatalytic spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
u	0071045	biological_process	nuclear histone mRNA catabolic process
u	0097526	cellular_component	spliceosomal tri-snRNP complex
u	1903241	biological_process	U2-type prespliceosome assembly
u	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN L 201

Chain	Residue
L	CYS6
L	CYS9
L	HIS24
L	HIS30

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EPE 1 201

Chain	Residue
L	HIS15
1	G11
1	G12
1	C13
1	C25
1	A26

---

site_id	AC3
Number of Residues	3
Details	binding site for residue MG 1 202

Chain	Residue
1	G130
1	MG203
1	MG207

---

site_id	AC4
Number of Residues	4
Details	binding site for residue MG 1 203

Chain	Residue
1	G132
1	MG202
1	MG206
1	MG207

---

site_id	AC5
Number of Residues	2
Details	binding site for residue MG 1 204

Chain	Residue
1	A126
1	MG206

---

site_id	AC6
Number of Residues	3
Details	binding site for residue MG 1 206

Chain	Residue
1	U131
1	MG203
1	MG204

---

site_id	AC7
Number of Residues	3
Details	binding site for residue MG 1 207

Chain	Residue
1	U128
1	MG202
1	MG203

---

site_id	AC8
Number of Residues	2
Details	binding site for residue MG 1 208

Chain	Residue
1	G130
B	GLU75

---

site_id	AC9
Number of Residues	2
Details	binding site for residue MG 1 209

Chain	Residue
1	A18
1	G19

---

site_id	AD1
Number of Residues	1
Details	binding site for residue K 1 210

Chain	Residue
1	U124

---

site_id	AD2
Number of Residues	1
Details	binding site for residue K b 101

Chain	Residue
b	GLU62

---

site_id	AD3
Number of Residues	1
Details	binding site for residue K b 102

Chain	Residue
b	GLN22

---

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN l 201

Chain	Residue
l	CYS6
l	CYS9
l	HIS24
l	HIS30

---

site_id	AD5
Number of Residues	3
Details	binding site for residue MG l 202

Chain	Residue
l	GLU32
l	ASN33
l	ASP36

---

site_id	AD6
Number of Residues	5
Details	binding site for residue EPE 2 201

Chain	Residue
2	G11
2	C13
2	A26
2	C27
l	HIS15

---

site_id	AD7
Number of Residues	1
Details	binding site for residue MG 2 203

Chain	Residue
1	U21

---

site_id	AD8
Number of Residues	1
Details	binding site for residue MG 2 204

Chain	Residue
2	G15

---

site_id	AD9
Number of Residues	1
Details	binding site for residue MG 2 205

Chain	Residue
2	U124

---

site_id	AE1
Number of Residues	2
Details	binding site for residue K Q 101

Chain	Residue
Q	SER73
n	THR58

---

site_id	AE2
Number of Residues	4
Details	binding site for residue ZN M 201

Chain	Residue
M	CYS6
M	CYS9
M	HIS24
M	HIS30

---

site_id	AE3
Number of Residues	2
Details	binding site for residue MG 3 201

Chain	Residue
3	A126
3	U127

---

site_id	AE4
Number of Residues	2
Details	binding site for residue MG 3 204

Chain	Residue
3	A18
3	G19

---

site_id	AE5
Number of Residues	4
Details	binding site for residue ZN m 201

Chain	Residue
m	CYS6
m	CYS9
m	HIS24
m	HIS30

---

site_id	AE6
Number of Residues	2
Details	binding site for residue EOH 4 201

Chain	Residue
4	A28
4	C29

---

site_id	AE7
Number of Residues	4
Details	binding site for residue CL 4 203

Chain	Residue
4	A135
4	U137
n	HIS34
n	GLN36

---

site_id	AE8
Number of Residues	3
Details	binding site for residue MG y 101

Chain	Residue
2	GTP1
y	C10
y	SO4103

---

site_id	AE9
Number of Residues	4
Details	binding site for residue MG y 102

Chain	Residue
m	HIS24
m	GLY27
m	HIS30
y	U4

---

site_id	AF1
Number of Residues	3
Details	binding site for residue SO4 y 103

Chain	Residue
2	GTP1
l	ASN33
y	MG101

---

site_id	AF2
Number of Residues	9
Details	binding site for Di-nucleotide GTP 2 1 and G 2 2

Chain	Residue
2	A3
4	GTP1
l	LYS29
l	GLU32
x	C9
x	C10
y	C10
y	MG101
y	SO4103

---

site_id	AF3
Number of Residues	8
Details	binding site for Di-nucleotide GTP 3 1 and G 3 2

Chain	Residue
1	GTP1
3	A3
3	HOH301
M	LYS29
M	GLU32
X	C10
Y	C9
Y	C10

---

site_id	AF4
Number of Residues	5
Details	binding site for Di-nucleotide GTP 4 1 and G 4 2

Chain	Residue
2	GTP1
4	A3
x	C10
y	C9
y	C10

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	792
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	316
Details	Region: {"description":"Sufficient for interaction with CLNS1A","evidences":[{"source":"PubMed","id":"11747828","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Lilla S.","von Kriegsheim A.","Lempens A.","Kolch W."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	128
Details	Zinc finger: {"description":"Matrin-type","evidences":[{"source":"HAMAP-Rule","id":"MF_03153","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---