4PJ9
Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 1 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | TCR-alpha | polymer | 203 | 22517.8 | 1 | Homo sapiens (Human) | ||
| 4 | D (D) | TCR-beta | polymer | 243 | 26908.9 | 1 | Homo sapiens (Human) | ||
| 5 | E (A) | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol | non-polymer | 316.3 | 1 | Chemie (2LJ) | |||
| 6 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 795 | Chemie (HOH) |
Sequence modifications
A: 1 - 270 (UniProt: Q95460)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93017.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 523.5 | |
| All* | Total formula weight | 93541.3 |
