4PID

Crystal structure of human adenovirus 2 protease with a weak pyrimidine nitrile inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protease	polymer	204	23114.3	1	UniProt (P03252) Pfam (PF00770) In PDB	Human adenovirus 2 (HAdV-2)	Adenain,Adenovirus protease,AVP,Adenovirus proteinase,Endoprotease
2	B	Pre-protein VI	polymer	11	1353.6	1	UniProt (P03274) In PDB	Human adenovirus 2	Protease cofactor,pVI-C
3	A	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	A	N-benzyl-2-[(Z)-iminomethyl]pyrimidine-5-carboxamide	non-polymer		240.3	1	Chemie (2UQ)
5		water	water		18.0	151	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24468.0
Non-Polymers*	Number of molecules	2
	Total formula weight	299.3
All*	Total formula weight	24767.3

*Water molecules are not included.