4PHL
TbrPDEB1-inhibitor complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Class 1 phosphodiesterase PDEB1 | polymer | 347 | 39093.7 | 2 | UniProt (Q8WQX9) Pfam (PF00233) In PDB | Trypanosoma brucei | |
2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE | non-polymer | 381.3 | 2 | Chemie (PIL) | |||
5 | A | GUANIDINE | non-polymer | 59.1 | 1 | Chemie (GAI) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | B | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
8 | water | water | 18.0 | 457 | Chemie (HOH) |
Sequence modifications
A, B: 576 - 918 (UniProt: Q8WQX9)
PDB | External Database | Details |
---|---|---|
His 572 | - | expression tag |
Met 573 | - | expression tag |
Ala 574 | - | expression tag |
Ser 575 | - | expression tag |
Gly 762 | Asp 762 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 78187.5 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1139.2 | |
All* | Total formula weight | 79326.6 |