Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
A | 0007165 | biological_process | signal transduction |
A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
B | 0007165 | biological_process | signal transduction |
B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue ZN A 1001 |
Chain | Residue |
A | HIS673 |
A | HIS709 |
A | ASP710 |
A | ASP822 |
A | HOH1143 |
A | HOH1259 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MG A 1002 |
Chain | Residue |
A | HOH1189 |
A | HOH1194 |
A | HOH1259 |
A | ASP710 |
A | HOH1155 |
A | HOH1164 |
site_id | AC3 |
Number of Residues | 15 |
Details | binding site for residue PIL A 1003 |
Chain | Residue |
A | MET785 |
A | ASP822 |
A | ILE823 |
A | ASN825 |
A | ALA837 |
A | VAL840 |
A | PHE844 |
A | GLY873 |
A | GLN874 |
A | GAI1004 |
A | HOH1179 |
A | HOH1250 |
A | HOH1284 |
A | HOH1288 |
A | HOH1304 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue GAI A 1004 |
Chain | Residue |
A | ASN717 |
A | PIL1003 |
A | HOH1195 |
A | HOH1202 |
A | HOH1304 |
site_id | AC5 |
Number of Residues | 8 |
Details | binding site for residue GOL A 1005 |
Chain | Residue |
A | TYR691 |
A | LEU694 |
A | HOH1139 |
A | HOH1141 |
A | HOH1231 |
B | TYR691 |
B | LEU694 |
B | GLU696 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue ZN B 1001 |
Chain | Residue |
B | HIS673 |
B | HIS709 |
B | ASP710 |
B | ASP822 |
B | HOH1208 |
B | HOH1289 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue MG B 1002 |
Chain | Residue |
B | ASP710 |
B | HOH1156 |
B | HOH1184 |
B | HOH1253 |
B | HOH1289 |
B | HOH1334 |
site_id | AC8 |
Number of Residues | 12 |
Details | binding site for residue PIL B 1003 |
Chain | Residue |
B | MET785 |
B | ASP822 |
B | ILE823 |
B | ASN825 |
B | ALA837 |
B | VAL840 |
B | PHE844 |
B | GLN874 |
B | HOH1210 |
B | HOH1230 |
B | HOH1273 |
B | HOH1275 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue EOH B 1004 |
Chain | Residue |
B | LYS723 |
B | GLN847 |
B | GLU851 |
B | LEU859 |
B | PHE862 |
Functional Information from PROSITE/UniProt
site_id | PS00126 |
Number of Residues | 12 |
Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
Chain | Residue | Details |
A | HIS709-PHE720 | |