4PCA

X-ray crystal structure of an O-methyltransferase from Anaplasma phagocytophilum bound to SAH and Manganese

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	O-methyltransferase family protein	polymer	226	25210.1	4	UniProt (S6G476)	Anaplasma phagocytophilum str. HGE1
2	E, H, K, P (A, B, C, D)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN) PubChem (27854)
3	F, I, L, Q (A, B, C, D)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (177678424) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (6419189) PubChem (52224398) PubChem (57544532) PubChem (164157219) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (126969526) PubChem (71170554) PubChem (129105892) PubChem (13231890) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	G, J, M, N, O... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	S, T, U, V (A, B, C, D)	water	water		18.0	982	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 218 (UniProt: S6G476)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	100840.4
Non-Polymers*	Number of molecules	14
	Total formula weight	2129.8
All*	Total formula weight	102970.2

*Water molecules are not included.