Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 301 |
| Chain | Residue |
| A | ASP136 |
| A | ASP162 |
| A | ASN163 |
| A | HOH412 |
| A | HOH443 |
| A | HOH501 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue SAH A 302 |
| Chain | Residue |
| A | THR65 |
| A | CYS66 |
| A | PHE69 |
| A | SER70 |
| A | GLU88 |
| A | LYS89 |
| A | ASN93 |
| A | GLY115 |
| A | GLU116 |
| A | ALA117 |
| A | ASP136 |
| A | ASN138 |
| A | TYR145 |
| A | HOH401 |
| A | HOH484 |
| A | HOH537 |
| A | HOH623 |
| B | SER33 |
| A | GLN39 |
| A | LEU40 |
| A | GLY64 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | GLN49 |
| A | ARG53 |
| A | HIS76 |
| A | HOH569 |
| A | HOH571 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 301 |
| Chain | Residue |
| B | ASP136 |
| B | ASP162 |
| B | ASN163 |
| B | HOH412 |
| B | HOH431 |
| B | HOH486 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | binding site for residue SAH B 302 |
| Chain | Residue |
| A | ASN182 |
| A | HOH405 |
| B | LEU35 |
| B | GLN39 |
| B | LEU40 |
| B | GLY64 |
| B | THR65 |
| B | CYS66 |
| B | PHE69 |
| B | SER70 |
| B | GLU88 |
| B | LYS89 |
| B | ASN93 |
| B | GLY115 |
| B | GLU116 |
| B | ALA117 |
| B | ASP136 |
| B | ASN138 |
| B | TYR145 |
| B | HOH478 |
| B | HOH530 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | GLN49 |
| B | ARG53 |
| B | HIS76 |
| B | HOH539 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 301 |
| Chain | Residue |
| B | HOH406 |
| B | HOH408 |
| C | ASP136 |
| C | ASP162 |
| C | ASN163 |
| C | HOH407 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | binding site for residue SAH C 302 |
| Chain | Residue |
| C | GLN39 |
| C | LEU40 |
| C | GLY64 |
| C | THR65 |
| C | CYS66 |
| C | PHE69 |
| C | SER70 |
| C | GLU88 |
| C | LYS89 |
| C | ASN93 |
| C | GLY115 |
| C | GLU116 |
| C | ALA117 |
| C | ASP136 |
| C | ASN138 |
| C | TYR145 |
| C | HOH486 |
| C | HOH517 |
| C | HOH563 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 303 |
| Chain | Residue |
| C | ALA55 |
| C | ARG154 |
| C | GLY156 |
| C | HOH611 |
| D | ARG53 |
| D | MET54 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 304 |
| Chain | Residue |
| C | GLN49 |
| C | ARG53 |
| C | HIS76 |
| C | HOH452 |
| C | HOH609 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 305 |
| Chain | Residue |
| C | HOH404 |
| C | HOH457 |
| D | GLN49 |
| D | ARG53 |
| D | HIS76 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 301 |
| Chain | Residue |
| D | ASP136 |
| D | ASP162 |
| D | ASN163 |
| D | HOH405 |
| D | HOH421 |
| D | HOH450 |
| site_id | AD4 |
| Number of Residues | 19 |
| Details | binding site for residue SAH D 302 |
| Chain | Residue |
| D | GLN39 |
| D | LEU40 |
| D | GLY64 |
| D | THR65 |
| D | CYS66 |
| D | PHE69 |
| D | SER70 |
| D | GLU88 |
| D | LYS89 |
| D | ASN93 |
| D | GLY115 |
| D | GLU116 |
| D | ALA117 |
| D | ASP136 |
| D | ASN138 |
| D | TYR145 |
| D | HOH459 |
| D | HOH478 |
| D | HOH490 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| C | GLU126 |
| C | HOH496 |
| D | ASN98 |
| D | ILE101 |
| D | GLU107 |
| D | ILE110 |
| D | HOH568 |
