4PAA
Crystal structure of the mature form of rat DMGDH complexed with tetrahydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dimethylglycine dehydrogenase | polymer | 848 | 95204.0 | 2 | UniProt (Q5RKL4) Pfam (PF01266) Pfam (PF16350) Pfam (PF01571) Pfam (PF08669) UniProt (by SIFTS) (Q63342) | Rattus norvegicus (Rat) | Dimethylglycine dehydrogenase,mitochondrial |
| 2 | C, E (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, F (A, B) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 2 | Chemie (THG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 857 (UniProt: Q5RKL4)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Ala 858 | - | expression tag |
| Ala 859 | - | expression tag |
| Leu 860 | - | expression tag |
| Glu 861 | - | expression tag |
| His 862 | - | expression tag |
| His 863 | - | expression tag |
| His 864 | - | expression tag |
| His 865 | - | expression tag |
| His 866 | - | expression tag |
| His 867 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 190408.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2462.0 | |
| All* | Total formula weight | 192870.0 |
