4P5K

Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HLA class II histocompatibility antigen, DP alpha 1 chain	polymer	183	21169.6	2	UniProt (P20036) Pfam (PF00993) Pfam (PF07654) In PDB	Homo sapiens (Human)	DP(W3),DP(W4),HLA-SB alpha chain,MHC class II DP3-alpha,MHC class II DPA1
2	B, E	RAS peptide,HLA class II histocompatibility antigen, DP beta 1 chain	polymer	212	24421.2	2	UniProt (Q5EP54) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P04440) In PDB	Homo sapiens

Sequence modifications

B, E: -25 - -14 (PDB: 4P5K)

PDB	External Database	Details
Gly -13	-	linker
Gly -12	-	linker
Ser -11	-	linker
Leu -10	-	linker
Val -9	-	linker
Pro -8	-	linker
Arg -7	-	linker
Gly -6	-	linker
Ser -5	-	linker
Gly -4	-	linker
Gly -3	-	linker
Gly -2	-	linker
Gly -1	-	linker

B, E: 3 - 189 (UniProt: Q5EP54)

PDB	External Database	Details
Ser 3	Thr 32	variant

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	91181.5
All*	Total formula weight	91181.5

*Water molecules are not included.