4P5H

Structure of Clostridium perfringens Enterotoxin with a peptide derived from a modified version of ECL-2 of Claudin 2

Replaces:  3ZJ3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	1, 2, 3, 4, P...	Claudin-2	polymer	20	2378.8	15	UniProt (O88552) In PDB	Mus musculus
2	A, B, C, D, E...	Heat-labile enterotoxin B chain	polymer	286	31524.0	15	UniProt (P01558) Pfam (PF03505) In PDB	Clostridium perfringens

Sequence modifications

1, 2, 3, 4, P, Q, R, S, T, U, V, W, X, Y, Z: 141 - 160 (UniProt: O88552)

PDB	External Database	Details
Asn 149	Ser 149	engineered mutation
Ala 155	Ser 155	engineered mutation

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O: 38 - 319 (UniProt: P01558)

PDB	External Database	Details
Gly 34	-	expression tag
Ala 35	-	expression tag
Met 36	-	expression tag
Gly 37	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	30
	Total formula weight	508541.0
All*	Total formula weight	508541.0

*Water molecules are not included.