4P57
MHC TCR peptide complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | HLA class II histocompatibility antigen, DP alpha 1 chain | polymer | 183 | 21169.6 | 2 | UniProt (P20036) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | DP(W3),DP(W4),HLA-SB alpha chain,MHC class II DP3-alpha,MHC class II DPA1 |
| 2 | B, D (B, D) | mim2 peptide,HLA class II histocompatibility antigen, DP beta 1 chain | polymer | 212 | 24394.2 | 2 | UniProt (Q5EP54) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P04440) | Homo sapiens (Human) | HLA class II histocompatibility antigen,DP(W2) beta chain,MHC class II antigen DPB1 |
| 3 | E, F, H, J, K (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I, L (B, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
B, D: -25 - -15 (PDB: 4P57)
B, D: 3 - 189 (UniProt: Q5EP54)
B, D: 3 - 189 (UniProt: Q5EP54)
| PDB | External Database | Details |
|---|---|---|
| Gly -14 | - | linker |
| Gly -13 | - | linker |
| Gly -12 | - | linker |
| Ser -11 | - | linker |
| Leu -10 | - | linker |
| Val -9 | - | linker |
| Pro -8 | - | linker |
| Arg -7 | - | linker |
| Gly -6 | - | linker |
| Ser -5 | - | linker |
| Gly -4 | - | linker |
| Gly -3 | - | linker |
| Gly -2 | - | linker |
| Gly -1 | - | linker |
| Ser 3 | Thr 32 | variant |
| Lys 69 | Glu 98 | engineered mutation |
| Lys 69 | Glu 98 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91127.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1278.3 | |
| All* | Total formula weight | 92405.9 |
