4P4S
GMPPCP-bound stalkless-MxA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced GTP-binding protein Mx1 | polymer | 303 | 32600.7 | 1 | UniProt (P20591) Pfam (PF00350) | Homo sapiens (Human) | Interferon-induced protein p78,IFI-78K,Interferon-regulated resistance GTP-binding protein MxA,Myxoma resistance protein 1,Myxovirus resistance protein 1 |
| 2 | B (B) | Interferon-induced GTP-binding protein Mx1 | polymer | 346 | 38539.2 | 1 | UniProt (P20591) Pfam (PF00350) Pfam (PF01031) | Homo sapiens (Human) | Interferon-induced protein p78,IFI-78K,Interferon-regulated resistance GTP-binding protein MxA,Myxoma resistance protein 1,Myxovirus resistance protein 1 |
| 3 | C, E (A, B) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 2 | Chemie (GCP) | |||
| 4 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 70 - 342 (UniProt: P20591)
B: 43 - 361 (UniProt: P20591)
B: 636 - 662 (UniProt: P20591)
| PDB | External Database | Details |
|---|---|---|
| Unk 52 | - | Remark 999 |
| Unk 53 | - | Remark 999 |
| Unk 54 | - | Remark 999 |
| Unk 55 | - | Remark 999 |
| Unk 56 | - | Remark 999 |
| Unk 57 | - | Remark 999 |
| Unk 58 | - | Remark 999 |
| Unk 59 | - | Remark 999 |
| Unk 60 | - | Remark 999 |
| Unk 61 | - | Remark 999 |
| Unk 62 | - | Remark 999 |
| Unk 63 | - | Remark 999 |
| Ser 322 | Cys 322 | engineered mutation |
| Ser 336 | Cys 336 | engineered mutation |
| Unk 343 | - | Remark 999 |
| Unk 344 | - | Remark 999 |
| Unk 345 | - | Remark 999 |
| Unk 346 | - | Remark 999 |
| Unk 347 | - | Remark 999 |
| Unk 348 | - | Remark 999 |
| Unk 349 | - | Remark 999 |
| Unk 350 | - | Remark 999 |
| Unk 351 | - | Remark 999 |
| Unk 352 | - | Remark 999 |
| Unk 353 | - | Remark 999 |
| Unk 354 | - | Remark 999 |
| Unk 355 | - | Remark 999 |
| Unk 356 | - | Remark 999 |
| Unk 357 | - | Remark 999 |
| Unk 358 | - | Remark 999 |
| Unk 359 | - | Remark 999 |
| Unk 360 | - | Remark 999 |
| PDB | External Database | Details |
|---|---|---|
| Ser 322 | Cys 322 | engineered mutation |
| Ser 336 | Cys 336 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 636 | Thr 636 | engineered mutation |
| Asp 637 | Ser 637 | engineered mutation |
| Pro 638 | Asp 638 | engineered mutation |
| Ala 640 | Arg 640 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71139.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1091.0 | |
| All* | Total formula weight | 72230.9 |
