4P4R
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | HLA class II histocompatibility antigen, DP alpha 1 chain | polymer | 183 | 21169.6 | 2 | UniProt (P20036) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (Human) | DP(W3),DP(W4),HLA-SB alpha chain,MHC class II DP3-alpha,MHC class II DPA1 |
2 | B, D | mim2 peptide,HLA class II histocompatibility antigen, DP beta 1 chain | polymer | 212 | 24394.2 | 2 | UniProt (P04440) Pfam (PF00969) Pfam (PF07654) In PDB | Homo sapiens | HLA class II histocompatibility antigen,DP(W4) beta chain,MHC class II antigen DPB1 |
3 | A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
4 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
B, D: -25 - -15 (PDB: 4P4R)
B, D: 3 - 189 (UniProt: P04440)
B, D: 3 - 189 (UniProt: P04440)
PDB | External Database | Details |
---|---|---|
Gly -14 | - | linker |
Gly -13 | - | linker |
Gly -12 | - | linker |
Ser -11 | - | linker |
Leu -10 | - | linker |
Val -9 | - | linker |
Pro -8 | - | linker |
Arg -7 | - | linker |
Gly -6 | - | linker |
Ser -5 | - | linker |
Gly -4 | - | linker |
Gly -3 | - | linker |
Gly -2 | - | linker |
Gly -1 | - | linker |
Ser 3 | Thr 32 | variant |
Val 36 | Ala 65 | variant |
Asp 55 | Ala 84 | variant |
Glu 56 | Ala 85 | variant |
Glu 69 | Lys 98 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 91127.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 884.8 | |
All* | Total formula weight | 92012.3 |