4P4G
Crystal Structure of Mycobacterium tuberculosis Shikimate Dehydrogenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase) | polymer | 277 | 28289.1 | 2 | UniProt (P95001) Pfam (PF08501) Pfam (PF18317) UniProt (by SIFTS) (I6Y120) | Mycobacterium tuberculosis | Shikimate 5-dehydrogenase |
| 2 | C (A) | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID | non-polymer | 174.2 | 1 | Chemie (SKM) PubChem (16758061) PubChem (1094) PubChem (21626190) PubChem (8742) PubChem (40970370) PubChem (42626655) PubChem (24202011) PubChem (49867941) PubChem (59081897) PubChem (69027491) PubChem (7076075) PubChem (10986763) PubChem (11332752) PubChem (11789701) PubChem (12315498) PubChem (12315501) | |||
| 3 | D, E, F, G, H... (A, B) | BROMIDE ION | non-polymer | 79.9 | 7 | Chemie (BR) PubChem (259) | |||
| 4 | J, K, M (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 495 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 269 (UniProt: P95001)
| PDB | External Database | Details |
|---|---|---|
| Leu 270 | - | expression tag |
| Asp 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56578.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1021.7 | |
| All* | Total formula weight | 57599.9 |
