4P3W
Crystal structure of the human filamin A Ig-like domains 20-21 in complex with migfilin peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (A, B, E, F, D...) | Filamin-A | polymer | 182 | 19023.2 | 6 | UniProt (P21333) Pfam (PF00630) | Homo sapiens (Human) | FLN-A,Actin-binding protein 280,ABP-280,Alpha-filamin,Endothelial actin-binding protein,Filamin-1,Non-muscle filamin |
| 2 | C, D, G, H, K... (G, H, K, L, J...) | Filamin-binding LIM protein 1 | polymer | 24 | 2613.0 | 6 | UniProt (Q8WUP2) | Homo sapiens | FBLP-1,Migfilin,Mitogen-inducible 2-interacting protein,MIG2-interacting protein |
| 3 | M, O, Q, U (A, B, E, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | N, P, S, T (A, B, E, D) | PRASEODYMIUM ION | non-polymer | 140.9 | 4 | Chemie (PR) | |||
| 5 | R, V (E, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | AA, BA, CA, DA, W... (F, D, C, I, A...) | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A, B, E, F, D, C: 2152 - 2329 (UniProt: P21333)
| PDB | External Database | Details |
|---|---|---|
| Gly 2148 | - | expression tag |
| Ala 2149 | - | expression tag |
| Met 2150 | - | expression tag |
| Gly 2151 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 129817.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 993.9 | |
| All* | Total formula weight | 130810.9 |
