4P2F

Monomeric form of a single mutant (F363R) of Mycobacterial Adenylyl cyclase Rv1625c

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Adenylate cyclase	polymer	273	29989.7	1	UniProt (P0A4Y0) Pfam (PF00211) UniProt (by SIFTS) (P9WQ35) In PDB	Mycobacterium tuberculosis	ATP pyrophosphate-lyase, Adenylyl cyclase
2	A	1,2-ETHANEDIOL	non-polymer		62.1	18	Chemie (EDO)
3	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	92	Chemie (HOH)

Sequence modifications

A: 212 - 443 (UniProt: P0A4Y0)

PDB	External Database	Details
Met 171	-	expression tag
Arg 172	-	expression tag
Gly 173	-	expression tag
Ser 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
Gly 181	-	expression tag
Met 182	-	expression tag
Ala 183	-	expression tag
Ser 184	-	expression tag
Met 185	-	expression tag
Thr 186	-	expression tag
Gly 187	-	expression tag
Gly 188	-	expression tag
Gln 189	-	expression tag
Gln 190	-	expression tag
Met 191	-	expression tag
Gly 192	-	expression tag
Arg 193	-	expression tag
Asp 194	-	expression tag
Leu 195	-	expression tag
Tyr 196	-	expression tag
Asp 197	-	expression tag
Asp 198	-	expression tag
Asp 199	-	expression tag
Asp 200	-	expression tag
Lys 201	-	expression tag
Asp 202	-	expression tag
Pro 203	-	expression tag
Ser 204	-	expression tag
Ser 205	-	expression tag
Arg 206	-	expression tag
Ser 207	-	expression tag
Ala 208	-	expression tag
Ala 209	-	expression tag
Gly 210	-	expression tag
Thr 211	-	expression tag
Arg 363	Phe 363	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29989.7
Non-Polymers*	Number of molecules	20
	Total formula weight	1315.4
All*	Total formula weight	31305.1

*Water molecules are not included.