4P24

pore forming toxin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Alpha-hemolysin	polymer	302	34305.1	7	UniProt (Q99UU6) Pfam (PF07968) UniProt (by SIFTS) (A0A0J9X1Z2)	Staphylococcus aureus subsp. aureus Mu50	Hla
2	H, I, J, K, L... (A, B, C, D, E...)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	13	Chemie (MPD)

Sequence modifications

A, B, C, D, E, F, G: 1 - 293 (UniProt: Q99UU6)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 179	Trp 205	engineered mutation
Ala 200	Arg 226	engineered mutation
Leu 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	240135.8
Non-Polymers*	Number of molecules	13
	Total formula weight	1536.3
All*	Total formula weight	241672.1

*Water molecules are not included.