4P24
pore forming toxin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0051715 | biological_process | cytolysis in another organism |
| A | 0090729 | molecular_function | toxin activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0051715 | biological_process | cytolysis in another organism |
| B | 0090729 | molecular_function | toxin activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0051715 | biological_process | cytolysis in another organism |
| C | 0090729 | molecular_function | toxin activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0031640 | biological_process | killing of cells of another organism |
| D | 0035821 | biological_process | modulation of process of another organism |
| D | 0051715 | biological_process | cytolysis in another organism |
| D | 0090729 | molecular_function | toxin activity |
| E | 0005576 | cellular_component | extracellular region |
| E | 0031640 | biological_process | killing of cells of another organism |
| E | 0035821 | biological_process | modulation of process of another organism |
| E | 0051715 | biological_process | cytolysis in another organism |
| E | 0090729 | molecular_function | toxin activity |
| F | 0005576 | cellular_component | extracellular region |
| F | 0031640 | biological_process | killing of cells of another organism |
| F | 0035821 | biological_process | modulation of process of another organism |
| F | 0051715 | biological_process | cytolysis in another organism |
| F | 0090729 | molecular_function | toxin activity |
| G | 0005576 | cellular_component | extracellular region |
| G | 0031640 | biological_process | killing of cells of another organism |
| G | 0035821 | biological_process | modulation of process of another organism |
| G | 0051715 | biological_process | cytolysis in another organism |
| G | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 401 |
| Chain | Residue |
| A | ASN176 |
| A | GLN177 |
| A | GLN194 |
| A | MET197 |
| A | LYS198 |
| A | THR199 |
| A | ALA200 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MPD A 402 |
| Chain | Residue |
| F | LEU116 |
| G | HIS144 |
| G | LEU146 |
| A | ALA179 |
| A | GLY180 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 403 |
| Chain | Residue |
| A | HIS144 |
| B | GLY180 |
| G | SER114 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue MPD B 401 |
| Chain | Residue |
| B | GLN194 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MPD C 401 |
| Chain | Residue |
| C | ASN176 |
| C | ALA179 |
| C | GLN194 |
| C | MET197 |
| C | LYS198 |
| C | ALA200 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue MPD C 402 |
| Chain | Residue |
| C | THR115 |
| C | LEU116 |
| D | HIS144 |
| D | LEU146 |
| E | ASN178 |
| E | ALA179 |
| E | GLY180 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MPD D 401 |
| Chain | Residue |
| D | ASN176 |
| D | GLN194 |
| D | MET197 |
| D | LYS198 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MPD D 402 |
| Chain | Residue |
| B | SER114 |
| C | HIS144 |
| D | ASN178 |
| D | ALA179 |
| D | GLY180 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MPD E 401 |
| Chain | Residue |
| E | ASN176 |
| E | GLN177 |
| E | ALA179 |
| E | GLN194 |
| E | MET197 |
| E | LYS198 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MPD F 401 |
| Chain | Residue |
| F | ASN176 |
| F | GLN194 |
| F | MET197 |
| F | LYS198 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue MPD F 402 |
| Chain | Residue |
| D | SER114 |
| D | LEU116 |
| F | GLY180 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MPD G 401 |
| Chain | Residue |
| G | ASN176 |
| G | TYR182 |
| G | GLN194 |
| G | MET197 |
| G | LYS198 |
| G | ALA200 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MPD G 402 |
| Chain | Residue |
| E | SER114 |
| F | LEU146 |
| G | ASN178 |
| G | ALA179 |
| G | GLY180 |
Functional Information from PROSITE/UniProt
| site_id | PS00274 |
| Number of Residues | 10 |
| Details | AEROLYSIN Aerolysin type toxins signature. TstNWkgTNT |
| Chain | Residue | Details |
| A | THR261-THR270 |
