4P10
pro-carboxypeptidase U In Complex With 5-(3-aminopropyl)-1-propyl-6,7-dihydro-4H-benzimidazole-5-carboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carboxypeptidase B2 | polymer | 404 | 46379.4 | 1 | UniProt (Q96IY4) Pfam (PF02244) Pfam (PF00246) | Homo sapiens (Human) | Carboxypeptidase U, CPU, Plasma carboxypeptidase B, pCPB, Thrombin-activable fibrinolysis inhibitor, TAFI |
| 2 | B (A) | (5R)-5-(3-aminopropyl)-1-propyl-4,5,6,7-tetrahydro-1H-benzimidazole-5-carboxylic acid | non-polymer | 265.4 | 1 | Chemie (2B8) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | F (A) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 23 - 423 (UniProt: Q96IY4)
| PDB | External Database | Details |
|---|---|---|
| Thr 347 | Ile 347 | conflict |
| Tyr 355 | His 355 | engineered mutation |
| Gln 357 | His 357 | engineered mutation |
| Leu 424 | - | expression tag |
| Glu 425 | - | expression tag |
| Pro 426 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46379.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 630.1 | |
| All* | Total formula weight | 47009.5 |
