4P0W
Human farnesyl diphosphate synthase in complex with Arenarone and zoledronate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl pyrophosphate synthase | polymer | 348 | 40029.7 | 1 | UniProt (P14324) Pfam (PF00348) | Homo sapiens (Human) | FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase |
| 2 | B (A) | 2-{[(1S,2R,4aS,8aR)-1,2,4a-trimethyl-5-methylidenedecahydronaphthalen-1-yl]methyl}cyclohexa-2,5-diene-1,4-dione | non-polymer | 312.4 | 1 | Chemie (1XH) | |||
| 3 | C (A) | ZOLEDRONIC ACID | non-polymer | 272.1 | 1 | Chemie (ZOL) | |||
| 4 | D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G (A) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40029.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 657.5 | |
| All* | Total formula weight | 40687.1 |
