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4OWF

Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NF-kappa-B essential modulatorpolymer9010648.22UniProt (O88522)
Pfam (PF16516)
Mus musculusNEMO, IkB kinase-associated protein 1, mFIP-3, Inhibitor of nuclear factor kappa-B kinase subunit gamma, IkB kinase subunit gamma, NF-kappa-B essential modifier, NEMO, IkB kinase-associated protein 1, mFIP-3, Inhibitor of nuclear factor kappa-B kinase subunit gamma, IkB kinase subunit gamma, NF-kappa-B essential modifier
2C
(G)
E3 ubiquitin-protein ligase RNF31polymer303316.81UniProt (Q96EP0)Homo sapiensHOIL-1-interacting protein, HOIP, RING finger protein 31, Zinc in-between-RING-finger ubiquitin-associated domain protein
3D
(G)
ZINC IONnon-polymer65.41Chemie (ZN)
4E, F, G
(A, B, G)
waterwater18.0100Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight24613.1
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight24678.5
*Water molecules are not included.

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PDB entries from 2025-06-25

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