4OV6
Crystal structure of PCSK9(53-451) with Adnectin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (A, D) | Proprotein convertase subtilisin/kexin type 9 | polymer | 93 | 10591.2 | 2 | UniProt (Q8NBP7) Pfam (PF05922) | Homo sapiens (human) | PCSK9, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
2 | B, D (B, E) | Proprotein convertase subtilisin/kexin type 9 | polymer | 294 | 31295.4 | 2 | UniProt (Q8NBP7) Pfam (PF00082) | Homo sapiens (human) | PCSK9, Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
3 | E, F (F, G) | Adnectin | polymer | 99 | 10864.0 | 2 | Pfam (PF00041) UniProt (by SIFTS) (A0A075B5G3) | Homo sapiens (human) | |
4 | G, H, I, L, M (A, B, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
5 | J, K (B, D) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
6 | N, O, P, Q, R... (A, B, D, E, F...) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 105501.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 698.8 | |
All* | Total formula weight | 106200.0 |