4ORI
Rat dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 372 | 40411.0 | 1 | UniProt (Q63707) Pfam (PF01180) | Rattus norvegicus (brown rat rat rats) | DHOdehase, Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D (A) | N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | non-polymer | 397.2 | 1 | Chemie (2V6) | |||
| 5 | E (A) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 33 - 396 (UniProt: Q63707)
| PDB | External Database | Details |
|---|---|---|
| Leu 397 | - | expression tag |
| Glu 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40411.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1009.7 | |
| All* | Total formula weight | 41420.6 |
