4ORI
Rat dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 372 | 40411.0 | 1 | UniProt (Q63707) Pfam (PF01180) In PDB | Rattus norvegicus (brown rat rat rats) | DHOdehase, Dihydroorotate oxidase |
2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
4 | A | N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | non-polymer | 397.2 | 1 | Chemie (2V6) | |||
5 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 33 - 396 (UniProt: Q63707)
PDB | External Database | Details |
---|---|---|
Leu 397 | - | expression tag |
Glu 398 | - | expression tag |
His 399 | - | expression tag |
His 400 | - | expression tag |
His 401 | - | expression tag |
His 402 | - | expression tag |
His 403 | - | expression tag |
His 404 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40411.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1009.7 | |
All* | Total formula weight | 41420.6 |