4OQG
Crystal structure of TEM-1 beta-lactamase in complex with boron-based inhibitor EC25
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ampicillin resistance protein | polymer | 263 | 28984.1 | 6 | UniProt (Q79DR3) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | Beta lactamase, Beta-lactamase, Betalactamase TEM-116, BlaTEM, Extended spectrum beta-lactamase, Mutant extended-spectrum beta-lactamase, TEM extended spectrum beta-lactamase |
| 2 | G, H, J, K, L (A, B, C, D, F) | 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid | non-polymer | 342.2 | 5 | Chemie (2UL) | |||
| 3 | I (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 173904.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1776.2 | |
| All* | Total formula weight | 175680.6 |
