4OQE
Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Fuc3NMe
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | polymer | 263 | 28537.9 | 2 | UniProt (P95748) Pfam (PF13649) In PDB | Streptomyces fradiae | Tylosin biosynthesis protein M1 |
2 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
3 | A, B | dTDP-3-N-methylamino-3,6-dideoxygalactose | non-polymer | 561.4 | 2 | Chemie (MMF) | |||
4 | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 255 (UniProt: P95748)
PDB | External Database | Details |
---|---|---|
Leu 256 | - | expression tag |
Glu 257 | - | expression tag |
His 258 | - | expression tag |
His 259 | - | expression tag |
His 260 | - | expression tag |
His 261 | - | expression tag |
His 262 | - | expression tag |
His 263 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57075.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1891.6 | |
All* | Total formula weight | 58967.3 |