4ONT
Ternary host recognition complex of complement factor H, C3d, and sialic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F, D, E | Complement factor H | polymer | 129 | 14773.8 | 3 | UniProt (P08603) Pfam (PF00084) In PDB | Homo sapiens (human) | H factor 1 |
2 | A, B, C | Complement C3d fragment | polymer | 317 | 35444.4 | 3 | UniProt (P01024) Pfam (PF07678) In PDB | Homo sapiens (human) | C3d |
3 | G, H, I | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 633.6 | 3 | In PDB GlyTouCan (G91237TK) | |||
4 | A, B, E, C | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
5 | water | water | 18.0 | 489 | Chemie (HOH) |
Sequence modifications
F, D, E: 1107 - 1231 (UniProt: P08603)
A, B, C: 3 - 310 (UniProt: P01024)
PDB | External Database | Details |
---|---|---|
Glu 1103 | - | expression tag |
Ala 1104 | - | expression tag |
Glu 1105 | - | expression tag |
Phe 1106 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Leu -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Pro -1 | - | expression tag |
Glu 0 | - | expression tag |
Phe 1 | - | expression tag |
Arg 2 | - | expression tag |
Ala 17 | Cys 1010 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 150654.7 | |
Branched | Number of molecules | 3 |
Total formula weight | 1900.7 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 644.7 | |
All* | Total formula weight | 153200.0 |