4ONS

Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Catenin alpha-2	polymer	248	27351.4	2	UniProt (Q61301) Pfam (PF01044)	Mus musculus (mouse)	Alpha N-catenin
2	B, D (B, D)	Catenin beta-1	polymer	88	9913.0	2	UniProt (Q02248)	Mus musculus (mouse)	Beta-catenin
3	E, F, G, H (A, B, C, D)	water	water		18.0	22	Chemie (HOH)

Sequence modifications

A, C: 18 - 264 (UniProt: Q61301)

PDB	External Database	Details
Met 17	-	expression tag

B, D: 78 - 151 (UniProt: Q02248)

PDB	External Database	Details
Met 64	-	expression tag
Gly 65	-	expression tag
Ser 66	-	expression tag
Ser 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
His 73	-	expression tag
Ser 74	-	expression tag
Gln 75	-	expression tag
Asp 76	-	expression tag
Pro 77	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	74528.7
All*	Total formula weight	74528.7

*Water molecules are not included.