4ONN

Crystal structure of human Mms2/Ubc13 - BAY 11-7082

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ubiquitin-conjugating enzyme E2 variant 2	polymer	153	17165.6	1	UniProt (Q15819) Pfam (PF00179)	Homo sapiens (human)	DDVit 1, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, MMS2 homolog, Vitamin D3-inducible protein
2	B (B)	Ubiquitin-conjugating enzyme E2 N	polymer	160	17942.6	1	UniProt (P61088) Pfam (PF00179)	Homo sapiens (human)	Bendless-like ubiquitin-conjugating enzyme, Ubc13, UbcH13, Ubiquitin carrier protein N, Ubiquitin-protein ligase N
3	C, D, F (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	E (B)	3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile	non-polymer		207.2	1	Chemie (BY1)
5	G, H (A, B)	water	water		18.0	183	Chemie (HOH)

Sequence modifications

A: 1 - 145 (UniProt: Q15819)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

B: 1 - 152 (UniProt: P61088)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Leu -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35108.2
Non-Polymers*	Number of molecules	4
	Total formula weight	483.5
All*	Total formula weight	35591.8

*Water molecules are not included.