4ONI
Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Nuclear receptor subfamily 5 group A member 2 | polymer | 253 | 29196.5 | 2 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (human) | Orphan nuclear receptor NR5A2, Alpha-1-fetoprotein transcription factor, B1-binding factor, hB1F, CYP7A promoter-binding factor, Hepatocytic transcription factor, Liver receptor homolog 1, LRH-1 |
| 2 | B, D (C, D) | Nuclear receptor subfamily 0 group B member 2 | polymer | 19 | 1948.3 | 2 | UniProt (Q15466) | Homo sapiens | Nuclear receptor NR0B2, Orphan nuclear receptor SHP, Small heterodimer partner |
| 3 | E (A) | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE | non-polymer | 709.9 | 1 | Chemie (EPH) | |||
| 4 | F, G, H (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | I (B) | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE | non-polymer | 747.0 | 1 | Chemie (P6L) | |||
| 6 | J (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 7 | K, L, M, N (A, C, B, D) | water | water | 18.0 | 352 | Chemie (HOH) |
Sequence modifications
A, B: 291 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ser 289 | - | expression tag |
| Asn 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62289.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1927.4 | |
| All* | Total formula weight | 64217.1 |
