4ONI
Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE EPH A 601 |
| Chain | Residue |
| A | PHE342 |
| A | TYR516 |
| A | LYS520 |
| A | HOH714 |
| A | MET345 |
| A | HIS390 |
| A | ILE416 |
| A | ALA420 |
| A | GLY421 |
| A | LEU424 |
| A | MET428 |
| A | ALA431 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 602 |
| Chain | Residue |
| A | GLN409 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 603 |
| Chain | Residue |
| A | LEU454 |
| A | SER458 |
| A | ASP460 |
| A | LEU503 |
| A | ARG507 |
| A | HOH702 |
| A | HOH705 |
| A | HOH718 |
| A | HOH867 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 604 |
| Chain | Residue |
| A | GLN351 |
| A | GLU358 |
| A | HOH857 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE P6L B 601 |
| Chain | Residue |
| B | PHE342 |
| B | MET345 |
| B | SER383 |
| B | ILE387 |
| B | HIS390 |
| B | ILE416 |
| B | GLN419 |
| B | ALA420 |
| B | GLY421 |
| B | LEU424 |
| B | LEU427 |
| B | MET428 |
| B | ALA513 |
| B | TYR516 |
| B | LEU517 |
| B | LYS520 |
| B | HOH718 |
| B | HOH835 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PG4 B 602 |
| Chain | Residue |
| B | LEU326 |
| B | GLN419 |
| B | HOH828 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 478 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Region: {"description":"AF-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15897460","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22187462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22504882","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26416531","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26553876","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ZDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3TX7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DOR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RWV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
