4OMP
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Proto-oncogene tyrosine-protein kinase Src | polymer | 76 | 8593.5 | 1 | UniProt (P00523) Pfam (PF00018) In PDB | Gallus gallus (bantam chickens) | Proto-oncogene c-Src, pp60c-src, p60-Src |
2 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
4 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 85 - 139 (UniProt: P00523)
PDB | External Database | Details |
---|---|---|
Met 64 | - | initiating methionine |
Gly 65 | - | expression tag |
Ser 66 | - | expression tag |
Ser 67 | - | expression tag |
His 68 | - | expression tag |
His 69 | - | expression tag |
His 70 | - | expression tag |
His 71 | - | expression tag |
His 72 | - | expression tag |
His 73 | - | expression tag |
Ser 74 | - | expression tag |
Ser 75 | - | expression tag |
Gly 76 | - | expression tag |
Leu 77 | - | expression tag |
Val 78 | - | expression tag |
Pro 79 | - | expression tag |
Arg 80 | - | expression tag |
Gly 81 | - | expression tag |
Ser 82 | - | expression tag |
His 83 | - | expression tag |
Met 84 | - | expression tag |
Lys 128 | Gln 128 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 8593.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 256.3 | |
All* | Total formula weight | 8849.8 |